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Free white paper gives comprehensive overview of how to reliably assess the quality of infant formula with ion chromatography.

Efficiently analyze food products with ion chromatography (IC). Discover its robust applications in quality control for beverages, food additives, and dairy.

Metrohm’s ST Raman technology enables fast, contactless identification of substances through opaque packaging, expanding safe, field-ready use of Raman spectroscopy.

This Application Note presents an electrochemiluminescence (ECL) method for a fast, accessible, and cost-effective alternative method to detect fentanyl.

This Process Application Note deals with online measurements of ammonia, nitrite, and nitrate in wastewater treatment plants. These nitrogen compounds are analyzed simultaneously using a drift-free colorimetric measurement in a multi-parameter process analyzer from Metrohm Process Analytics.

Calcium carbonate has a wide applicability in the pharmaceutical industry as an excipient and also as an active ingredient, and in the food industry as a major dietary supplement. The U.S. Pharmacopoeia (USP) monographs for calcium and magnesium carbonates tablets as well as calcium carbonate and magnesia chewable tablets currently describe manual titration as the assay procedure for calcium and magnesium. The USP has embarked on a global initiative to modernize many of the existing monographs across all compendia. In response to this initiative, two alternative analytical methods were developed to determine the analytes calcium and magnesium. This Application Note presents ion chromatography (IC) procedures using conductivity detection that provide better accuracy and specificity and are suitable for the intended purpose. These validated IC methods (according to USP General Chapter <1225>) offer a significant improvement to the existing assays because they can simultaneously determine both analytes calcium and magnesium, saving both time and effort.

Kjeldahl method is used to determine the nitrogen content in organic and inorganic samples. Kjeldahl consists of three steps: digestion, distillation, and titration. During the catalytic digestion step, organic nitrogen is converted into ammonium. Sodium hydroxide is added just before the distillation step for converting ammonium into ammonia. Through steam distillation the latter is transferred into the receiver vessel containing an absorbing agent (e.g., boric acid). Finally, the separated ammonia is titrated against sulfuric acid. Protein content in samples can also be determined from the nitrogen content obtained by Kjeldahl setup. USP describes the titration method to determine nitrogen content in organic products using Kjeldahl nitrogen setup. This Application Note illustrates nitrogen determination in heparin sodium.

This Application Note details the determination of acid-neutralizing capacity (ANC) in several pharmaceutical samples in compliance with USP<301> standards.

Precise online monitoring of peracetic acid (PPA) for beverage bottling requires a reliable stainless steel process analyzer.

Salmon farms are becoming ever more popular. Strong population growth increases the demand for salmon which has an effect on their cultivation. Ever more fish live in limited space in open net cages. Parasites such as salmon lice can multiply quickly due to the high density of fish. One possibility of fighting the lice is to use baths with weak concentrations of H2O2. The salmon are treated in these concentrations for up to 20 minutes until the lice fall away and die. While it is true that hydrogen peroxide decomposes relatively quickly, it is nonetheless deadly for salmon in higher concentrations. The concentration must therefore always lie within the specifications during treatment. Our process analyzer requires less than two minutes per titration. This means that it permits more concentration determinations per treatment and always guarantees the correct dosage.

Incineration flue gas requires treatment such as wet scrubbing. The 2060 VA Process Analyzer monitors heavy metals in the scrubbing water, ensuring compliance.

In severe cases of cyanide poisoning, sodium nitrite is used along with sodium thiosulfate for treatment. This Application Note describes the nitrite ion chromatography assay with the Metrosep A Supp 4 column and suppressed conductivity detection. This column equivalency study was in cooperation with the USP according to the USP General Chapter <621>.

Potassium citrate and citric acid oral solutions act as systemic alkalizers. Potassium assays, validated per USP <621> and <1225>, use IC with L76 cation-exchange columns.

This Application Note presents an update to the standard AOAC method for total GOS determination in foodstuffs.

In power plants, corrosion is the greatest enemy. If corrosive impurities are present in the circuit streams (e.g., chlorides and hydroxides), deposition of an insulating layer of scale on the heat transfer surfaces occurs, resulting in costly and critical downtimes. To ensure high throughput of power plants, online analysis of critical parameters such as sodium is highly advantageous for safety, protection, and process optimization. With the 2035 Process Analyzer from Metrohm Process Analytics, operators gain the information they need to accurately identify trends, reduce downtimes, and address operational issues before costly problems arise.

This Application Note discusses differential capacity analysis (DCA) and its impact on enhancing battery performance, with a focus on using the INTELLO platform.

Advances in polymeric membranes and screen-printed technologies have enabled miniaturized, portable potentiometric sensors ideal for point-of-care analysis.