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Trace analysis of glyphosate and AMPA with IC

40 min

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Dr. Andrea Wille from Metrohm International Headquarters describes how glyphosate and its metabolite AMPA (Aminomethanphosphonic acid) can be analyzed by IC with amperometric detection.

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A reliable and cost-effective alternative

Tractor in a field spraying herbicides, glyphosate and AMPA

Usually, glyphosate and its metabolite AMPA are determined by High-Performance Liquid Chromatography (HPLC) with post-column derivatization and subsequent fluorescence detection (EPA Method 547), or alternatively by ion chromatography coupled with a mass-selective detector.

The following blog article outlines the determination of glyphosate and AMPA in drinking water in the low µg/L range using ion chromatography with pulsed amperometric detection (flexIPAD). This technique proved to be a reliable and, compared with HPLC, inexpensive method for determining the glyphosate and AMPA content in water and foodstuffs.

Blog: Measuring herbicides in drinking water

Glyphosate and AMPA determination with IC

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This white paper outlines glyphosate determination and that of its primary metabolite AMPA in drinking water using IC with pulsed amperometric detection (flexIPAD) in the low µg/L range. Compared to HPLC analysis with a mass-selective detector, it is a very cost-effective method for determining the glyphosate and AMPA content in water and foodstuffs. With a detection limit at approx. 1 µg/L, compliance with limit values for glyphosate can be monitored in the USA, Canada, and Australia, among others.