Simultaneous Determination of Anions and Disinfection By-Products (EPA 300.1) using Hydroxide as the Eluent
Summary
Simultaneous determination of anions and disinfection by-products (DBPs) in water using EPA 300.1 is often performed using separate methods for Part A and Part B, which can increase analysis time and complexity.
This application note presents a single ion chromatography method using hydroxide eluent generated by a 948 CEP module to combine both parts into one run.
The method provides low ppb detection limits and strong resolution of key analytes such as chlorite and bromate, even in the presence of high chloride concentrations. Minimal sample preparation is required, and the system uses conductivity detection for all analytes.
Additional validation demonstrates good repeatability and acceptable spike recoveries within EPA 300.1 limits, confirming method accuracy across various water matrices.
